| Peer-Reviewed

Prognostic Analysis of Acute Pancreatitis with Fatty Liver

Received: 4 March 2020     Published: 19 May 2020
Views:       Downloads:
Abstract

Objective: To investigate the effects of fatty liver on the progression and prognosis of acute pancreatitis. METHODS: 538 patients with acute pancreatitis admitted to our department from January 2014 to September 2018 were enrolled, including 210 patients with fatty liver disease and 328 patients without fatty liver. The two groups were retrospectively analyzed to analyze the disease of the two groups. There were no differences in progression, morbidity, and average hospitalization days. Results: 1. The proportion of patients with severe pancreatitis in the fatty liver group was higher than that in the non-fatty liver group (P<0.01). 2. The incidence of complications in the fatty liver group was higher than that in the non-fatty liver group (P<0.01). The average hospitalization period of the fatty liver group was longer than that of the non-fatty liver group (P<0.01). There was no clear correlation between the severity of fatty liver and the severity of pancreatitis (P>0.05). Conclusion: The prognosis of patients with acute pancreatitis complicated with fatty liver is worse than that of patients with simple pancreatitis. The incidence of complications is increased and the hospitalization period is prolonged. Fatty liver is a high risk factor for the progression and prognosis of acute pancreatitis.

Published in Science Discovery (Volume 8, Issue 1)
DOI 10.11648/j.sd.20200801.16
Page(s) 24-26
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Fatty Liver, Acute Pancreatitis, Prognosis

References
[1] 祝荫,吕农华.重视急性胰腺炎病因的诊治[J].中华消化杂志,2019,39(1):68-70.
[2] 张文凯,李长罗,柴湘平.高脂血症性急性胰腺炎的研究进展[J].中国急救复苏与灾害医学杂志,2018,13(2):189-192.
[3] 朱学进.高脂血症与急性胰腺炎的关系及对预后的影响[J].临床医学研究与实践,2018,3(9):48-49.
[4] Lee SW, Lee TY, Yang SS, et al. The association of non-alcoholic fatty liver disease and metabolic syndrome in a Chinese population [J]. Hepatobiliary Pancreat Dis Int. 2017, 16 (2): 176-180.
[5] Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus [J]. Gut. 2013, 62 (1): 102–11.
[6] Limanond P, Raman SS, Lassman C, et al. Macrovesicular hepatic steatosis in living related liver donors: correlation between CT and histologic findings [J]. Radiology. 2004, 230 (1): 276–80.
[7] Fan JG, Epidemiology of alcoholic and nonalcoholic fatty liver disease in China [J]. J Gastroenterol Hepatol. 2013, 28, Suppl 1: 11–17.
[8] Bedogni G, Nobili V, Tiribelli C.Epidemiology of fatty liver: an update [J]. World J Gastroenterol. 2014, 20 (27): 9050–4.
[9] Yoon SB, Lee IS, Choi MH, et al. Impact of Fatty Liver on Acute Pancreatitis Severity [J]. Gastroenterol Res Pract. 2017, 2017: 4532320.
[10] 谭书德,李恩春,代志昌,等.急性胰腺炎与脂肪肝关系分析[J].中华临床医师杂志(电子版),2012,6(3):772-774.
[11] 吴迪,宋玲玲,赵艳辉.脂肪肝与急性胰腺炎分级的关系研究[J].中国实验诊断学,2018,22(9):1557-1559.
[12] 张帆,郭强,张渊智.高脂血症、微循环障碍与急性胰腺炎关系的探讨[J].胃肠病学和肝病学杂志,2011,20(3):275-278.
[13] Guo YY, Li HX, Zhang Y, et al. Hypertriglyceridemia-induced Acute Pancreatitis: Progress on Disease Mechanisms and Treatment Modalities [J]. Discov Med. 2019, 27 (147): 101-109.
[14] 高帆,祁兴顺,侯悦,等.胰腺炎与脂肪肝的关系探讨[J]. 临床肝胆病杂志, 2017(1):40-45.
Cite This Article
  • APA Style

    Jingyi Liu, Dongyuan Su. (2020). Prognostic Analysis of Acute Pancreatitis with Fatty Liver. Science Discovery, 8(1), 24-26. https://doi.org/10.11648/j.sd.20200801.16

    Copy | Download

    ACS Style

    Jingyi Liu; Dongyuan Su. Prognostic Analysis of Acute Pancreatitis with Fatty Liver. Sci. Discov. 2020, 8(1), 24-26. doi: 10.11648/j.sd.20200801.16

    Copy | Download

    AMA Style

    Jingyi Liu, Dongyuan Su. Prognostic Analysis of Acute Pancreatitis with Fatty Liver. Sci Discov. 2020;8(1):24-26. doi: 10.11648/j.sd.20200801.16

    Copy | Download

  • @article{10.11648/j.sd.20200801.16,
      author = {Jingyi Liu and Dongyuan Su},
      title = {Prognostic Analysis of Acute Pancreatitis with Fatty Liver},
      journal = {Science Discovery},
      volume = {8},
      number = {1},
      pages = {24-26},
      doi = {10.11648/j.sd.20200801.16},
      url = {https://doi.org/10.11648/j.sd.20200801.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20200801.16},
      abstract = {Objective: To investigate the effects of fatty liver on the progression and prognosis of acute pancreatitis. METHODS: 538 patients with acute pancreatitis admitted to our department from January 2014 to September 2018 were enrolled, including 210 patients with fatty liver disease and 328 patients without fatty liver. The two groups were retrospectively analyzed to analyze the disease of the two groups. There were no differences in progression, morbidity, and average hospitalization days. Results: 1. The proportion of patients with severe pancreatitis in the fatty liver group was higher than that in the non-fatty liver group (P0.05). Conclusion: The prognosis of patients with acute pancreatitis complicated with fatty liver is worse than that of patients with simple pancreatitis. The incidence of complications is increased and the hospitalization period is prolonged. Fatty liver is a high risk factor for the progression and prognosis of acute pancreatitis.},
     year = {2020}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Prognostic Analysis of Acute Pancreatitis with Fatty Liver
    AU  - Jingyi Liu
    AU  - Dongyuan Su
    Y1  - 2020/05/19
    PY  - 2020
    N1  - https://doi.org/10.11648/j.sd.20200801.16
    DO  - 10.11648/j.sd.20200801.16
    T2  - Science Discovery
    JF  - Science Discovery
    JO  - Science Discovery
    SP  - 24
    EP  - 26
    PB  - Science Publishing Group
    SN  - 2331-0650
    UR  - https://doi.org/10.11648/j.sd.20200801.16
    AB  - Objective: To investigate the effects of fatty liver on the progression and prognosis of acute pancreatitis. METHODS: 538 patients with acute pancreatitis admitted to our department from January 2014 to September 2018 were enrolled, including 210 patients with fatty liver disease and 328 patients without fatty liver. The two groups were retrospectively analyzed to analyze the disease of the two groups. There were no differences in progression, morbidity, and average hospitalization days. Results: 1. The proportion of patients with severe pancreatitis in the fatty liver group was higher than that in the non-fatty liver group (P0.05). Conclusion: The prognosis of patients with acute pancreatitis complicated with fatty liver is worse than that of patients with simple pancreatitis. The incidence of complications is increased and the hospitalization period is prolonged. Fatty liver is a high risk factor for the progression and prognosis of acute pancreatitis.
    VL  - 8
    IS  - 1
    ER  - 

    Copy | Download

Author Information
  • Department of Gastroenterology, Chongzhou People's Hospital, Chengdu, China

  • Department of Gastroenterology, Chongzhou People's Hospital, Chengdu, China

  • Sections