The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis

Ding Ning; Dong Anqin; Zhang Cuicui; Zhang Lingxi

doi:doi:10.11648/j.sd.20221002.16

| Peer-Reviewed

The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis

Ding Ning, Dong Anqin, Zhang Cuicui, Zhang Lingxi

Published in Science Discovery (Volume 10, Issue 2)

Received: 16 March 2022 Accepted: 15 April 2022 Published: 22 April 2022

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Objective: A systematic review of the effectiveness of cognitive behavioral therapy (CBT) and traditional non-drug methods in the treatment of neuropathic pain and anxiety. Method: PubMed, Embase, Cochrane, PsycINFO, Wanfang Database (WANFANG), China Knowledge Network (CNKI), VIP (VIP) and China Biomedical Literature Database (CBM) were electronically searched from the establishment of the database to March 2021 to collect randomized controlled trials (RCT) of the treatment of neuropathic pain. Two researchers independently carried out literature screening, data extraction and methodological quality evaluation, and cross-checked, and used RevMan5.3 software for Meta analysis. Results: A total of 15 RCTs with 1274 subjects were included, including 606 cases in the CBT group and 668 cases in the traditional treatment group. Meta-analysis results show that, compared with traditional non-drug treatments, CBT can significantly reduce neuropathic pain scores (MD=-0.55, 95%CI=-0.81~-0.29), and improve patients’ depression and anxiety (Baker Depression Scale), MD=-2.23, 95%CI=-3.84~-0.82; Hamilton Anxiety Scale, MD=-4.25, 95%CI=-6.20~-2.29). Conclusion: Current evidence shows that CBT has a good clinical effect on reducing neuropathic pain and improving patients' depression and anxiety. It can be used as a non-drug treatment for neuropathic pain in clinics, communities and families.

Published in	Science Discovery (Volume 10, Issue 2)
DOI	10.11648/j.sd.20221002.16
Page(s)	60-67
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Cognitive Behavioral Therapy, Neuropathic Pain, Meta Analysis

References

[1]	Treede RD, Jensen TS, Campbell JN, et al. Neuropathic pain: redefinition and a grading system for clinical and research purposes [J]. Neurology, 2008, 70(18): 1630-1635.
[2]	迟宏杰,陈丽霞.正念干预缓解慢性疼痛的效果及其机制[J].中华行为医学与脑科学杂志, 2019, 28 (9): 802-805。
[3]	Van Hecke O, Austin SK, Khan RA, et al. Neuropathic pain in the general population: a systematic review of epidemiological studies [J]. Pain, 2014, 155 (4): 654-662.
[4]	刘俊,高峰,李迪,等.脊髓损伤后神经病理性疼痛机制的研究进展[J].中国康复, 2020, 35 (9): 488-491。
[5]	神经病理性疼痛诊疗专家组.神经病理性疼痛诊疗专家共识[J].中国疼痛医学杂志, 2013, 19 (12): 705-710。
[6]	Gunnarsdottir S, Ward SE, Serlin RC. A population based study of the prevalence of pain in Iceland [J]. Scandinavian journal of pain, 2010, 1 (3): 151-157.
[7]	王倩,王德强,孙书勤.癌痛康复治疗进展[J].中国康复医学杂志, 2018, 33 (12): 1498-1501。
[8]	吴庭胜,范少勇,华鸿,等.腰交感神经阻滞在下肢神经病理性疼痛患者的临床价值分析[J].医学理论与实践, 2020, 33 (8): 1293-1294。
[9]	王蕊,于洋,陈付强.脊髓电刺激治疗带状疱疹后神经痛疗效的临床研究[J].中国疼痛医学杂志, 2017, 23 (8): 616-618,621。
[10]	Wong WS, Lam HM, Chow YF, et al. The effects of anxiety sensitivity, pain hypervigilance, and pain catastrophizing on quality of life outcomes of patients with chronic pain: a preliminary, cross-sectional analysis [J]. Quality of life research: an international journal of quality of life aspects of treatment, care and rehabilitation, 2014, 23 (8): 2333-2341.
[11]	Poulin PA, Romanow HC, Rahbari N, et al. The relationship between mindfulness, pain intensity, pain catastrophizing, depression, and quality of life among cancer survivors living with chronic neuropathic pain [J]. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer, 2016, 24 (10): 4167-4175.
[12]	盛海燕,张玉秋.慢性痛引起的认知和情感变化[J].中国疼痛医学杂志, 2019, 25 (12): 885-889。
[13]	J Katz RM. The McGill Pain Questionnaire: Development, Psychometric Properties, and Usefulness of the Long Form, Short Form, and Short Form-2 [J]. 2011
[14]	伍琳,张雷鸣,张剑宁,等. 认知疗法在椎间孔镜手术病人护理中的应用[J]. 中国疼痛医学杂志, 2019, 25 (2): 157-160。
[15]	Bernardy K, Füber N, Köllner V, et al. Efficacy of cognitive-behavioral therapies in fibromyalgia syndrome - a systematic review and metaanalysis of randomized controlled trials [J]. The Journal of rheumatology, 2010, 37 (10): 1991-2005.
[16]	Tatrow K, Montgomery GH. Cognitive behavioral therapy techniques for distress and pain in breast cancer patients: a meta-analysis [J]. Journal of behavioral medicine, 2006, 29 (1): 17-27.
[17]	屈云,何俐,刘鸣.Cochrane系统评价的基本方法[J].中国临床康复, 2003, 7 (4): 532-533,536。
[18]	Gale G, Nussbaum D, Rothbart P, et al. A randomized treatment study to compare the efficacy of repeated nerve blocks with cognitive therapy for control of chronic head and neck pain [J]. Pain research & management, 2002, 7 (4): 185-189.
[19]	Wetherell JL, Afari N, Rutledge T, et al. A randomized, controlled trial of acceptance and commitment therapy and cognitive-behavioral therapy for chronic pain [J]. Pain, 2011, 152 (9): 2098-2107.
[20]	Otis JD, Sanderson K, Hardway C, et al. A randomized controlled pilot study of a cognitive-behavioral therapy approach for painful diabetic peripheral neuropathy [J]. Journal of Pain, 2013, 14 (5): 475-482.
[21]	Higgins DM, Heapy AA, Buta E, et al. A randomized controlled trial of cognitive behavioral therapy compared with diabetes education for diabetic peripheral neuropathic pain [J]. Journal of health psychology, 2020, 1359105320962262.
[22]	刘振东.认知行为疗法对伴慢性疼痛的老年抑郁症患者生存质量的影响[J].中华行为医学与脑科学杂志, 2011, 20 (9): 830-832。
[23]	朱莲芳.认知行为干预对腰椎间盘突出症患者疼痛水平及自我效能的影响[J].当代护士（上旬刊）, 2019, 26 (11): 54-56。
[24]	杨亚娟.认知行为疗法对骨关节炎患者的护理干预效果研究[J].医药前沿, 2015 (13): 262-264。
[25]	Heutink M, Post MW, Bongers-Janssen HM, et al. The CONECSI trial: results of a randomized controlled trial of a multidisciplinary cognitive behavioral program for coping with chronic neuropathic pain after spinal cord injury [J]. Pain, 2012, 153 (1): 120‐128.
[26]	Evans S, Fishman B, Spielman L, et al. Randomized trial of cognitive behavior therapy versus supportive psychotherapy for HIV-related peripheral neuropathic pain [J]. Psychosomatics, 2003, 44 (1): 44-50.
[27]	Hasenbring M, Ulrich HW, Hartmann M, et al. The efficacy of a risk factor-based cognitive behavioral intervention and electromyographic biofeedback in patients with acute sciatic pain. An attempt to prevent chronicity [J]. Spine, 1999, 24 (23): 2525-2535.
[28]	Dehestani M, Mirzaian B, Saadat P. The effectiveness of cognitive – behavioral group therapy on pain perception and pain severity among patients with chronic neuropathic pain [J]. Journal of Babol University of Medical Sciences, 2019, 21 (1): 61-66.
[29]	武绍远,钟静玫,陈辉,等.抗抑郁药配合认知行为治疗持续性躯体形式疼痛障碍初步报告[J].中国神经精神疾病杂志, 2006, 32 (4): 365-367。
[30]	常国胜,倪居,张瑞星,等.暗示疗法与认知行为疗法在老年躯体形式疼痛障碍患者中的效果比较[J].中国老年学杂志, 2016, 36 (20): 5110-5111, 5112。
[31]	王平,郭奕倩,王效敏.短程小组认知行为治疗失眠伴慢性非恶性颈背痛的效果[J].中国医药导报, 2015, 12 (14): 61-65。
[32]	冯丽娜.认知行为干预对脊柱外科手术患者围手术期不良情绪及疼痛的影响[J].护理实践与研究, 2019, 16 (18): 61-63。
[33]	Eccleston C, Hearn L, Williams AC. Psychological therapies for the management of chronic neuropathic pain in adults [J]. The Cochrane database of systematic reviews, 2015 (10): Cd011259.
[34]	Warth M, Zöller J, Köhler F, et al. Psychosocial Interventions for Pain Management in Advanced Cancer Patients: a Systematic Review and Meta-analysis [J]. Current oncology reports, 2020, 22 (1): 3.
[35]	Twiddy H, Frank B, Alam U. A Consideration of the Psychological Aspects to Managing Patients with Painful Diabetic Neuropathy: An Insight into Pain Management Services at a Tertiary Centre in the UK [J]. Diabetes therapy: research, treatment and education of diabetes and related disorders, 2021, 12 (2): 487-498.
[36]	疼痛新定义[J].中国疼痛医学杂志, 2016, 22 (11): 808-809。
[37]	Gerrits MM, van Marwijk HW, van Oppen P, et al. Longitudinal association between pain, and depression and anxiety over four years [J]. Journal of psychosomatic research, 2015, 78 (1): 64-70.
[38]	Hooten WM. Chronic Pain and Mental Health Disorders: Shared Neural Mechanisms, Epidemiology, and Treatment [J]. Mayo Clinic proceedings, 2016, 91 (7): 955-970.
[39]	Ligthart L, Visscher CM, van Houtem CM, et al. Comorbidity among multiple pain symptoms and anxious depression in a Dutch population sample [J]. The journal of pain, 2014, 15 (9): 945-955.
[40]	邵芳冰,房军帆,王思思,等.慢性痛诱发痛焦虑抑郁样情绪动物模型及其行为学评价概述[J].中国疼痛医学杂志, 2020, 26 (10): 763-768。
[41]	马玲,倪家骧.慢性疼痛与抑郁症状的研究进展[J].中国康复医学杂志, 2008, 23 (11): 1053-1056。
[42]	陈龙梅,王珩.腰椎间盘突出症患者抑郁、焦虑状况及影响因素分析[J].中国疼痛医学杂志, 2014, 20 (6): 437-440。
[43]	中国医师协会神经内科医师分会疼痛与感觉障碍学组.偏头痛与抑郁障碍共病诊治中国专家共识[J].中国疼痛医学杂志, 2020, 26 (12): 881-890。
[44]	韩丽霞,韩冰.认知行为干预对抑郁症的影响[J].中国康复, 2012, 27 (2): 102-103。
[45]	Kroenke K, Bair MJ, Damush TM, et al. Optimized antidepressant therapy and pain self-management in primary care patients with depression and musculoskeletal pain: a randomized controlled trial [J]. Jama, 2009, 301 (20): 2099-2110.
[46]	Nicholas MK, Asghari A, Corbett M, et al. Is adherence to pain self-management strategies associated with improved pain, depression and disability in those with disabling chronic pain? [J]. European journal of pain (London, England), 2012, 16 (1): 93-104.
[47]	张星星,周晨,段宏为,等.认知行为疗法减轻帕金森病患者抑郁或焦虑的Meta分析[J].中国全科医学, 2019, 22 (17): 2084-2090。
[48]	Chavooshi B, Saberi M, Tavallaie SA, et al. Psychotherapy for Medically Unexplained Pain: A Randomized Clinical Trial Comparing Intensive Short-Term Dynamic Psychotherapy and Cognitive-Behavior Therapy [J]. Psychosomatics, 2017, 58 (5): 506-518.
[49]	李晋娜,贾龙斌,许丽娜,等. 认知行为疗法联合药物治疗卒中后抑郁的临床观察[J]. 中国药物与临床, 2020, 20 (22): 3713-3716。
[50]	Sonenberg N, Hinnebusch AG. Regulation of translation initiation in eukaryotes: Mechanisms and biological targets. Cell 2009; 136 (4): 731–45.
[51]	Zabihiyeganeh M, Vafaee Afshar S, Amini Kadijani A, et al. The effect of cognitive behavioral therapy on the circulating proinflammatory cytokines of fibromyalgia patients: A pilot controlled clinical trial. Gen Hosp Psychiatry 2019; 57: 23–8.

Cite This Article

Plain Text BibTeX RIS

APA Style

Ding Ning, Dong Anqin, Zhang Cuicui, Zhang Lingxi. (2022). The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis. Science Discovery, 10(2), 60-67. https://doi.org/10.11648/j.sd.20221002.16

Copy | Download

ACS Style

Ding Ning; Dong Anqin; Zhang Cuicui; Zhang Lingxi. The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis. Sci. Discov. 2022, 10(2), 60-67. doi: 10.11648/j.sd.20221002.16

Copy | Download

AMA Style

Ding Ning, Dong Anqin, Zhang Cuicui, Zhang Lingxi. The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis. Sci Discov. 2022;10(2):60-67. doi: 10.11648/j.sd.20221002.16

Copy | Download

@article{10.11648/j.sd.20221002.16,
  author = {Ding Ning and Dong Anqin and Zhang Cuicui and Zhang Lingxi},
  title = {The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis},
  journal = {Science Discovery},
  volume = {10},
  number = {2},
  pages = {60-67},
  doi = {10.11648/j.sd.20221002.16},
  url = {https://doi.org/10.11648/j.sd.20221002.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20221002.16},
  abstract = {Objective: A systematic review of the effectiveness of cognitive behavioral therapy (CBT) and traditional non-drug methods in the treatment of neuropathic pain and anxiety. Method: PubMed, Embase, Cochrane, PsycINFO, Wanfang Database (WANFANG), China Knowledge Network (CNKI), VIP (VIP) and China Biomedical Literature Database (CBM) were electronically searched from the establishment of the database to March 2021 to collect randomized controlled trials (RCT) of the treatment of neuropathic pain. Two researchers independently carried out literature screening, data extraction and methodological quality evaluation, and cross-checked, and used RevMan5.3 software for Meta analysis. Results: A total of 15 RCTs with 1274 subjects were included, including 606 cases in the CBT group and 668 cases in the traditional treatment group. Meta-analysis results show that, compared with traditional non-drug treatments, CBT can significantly reduce neuropathic pain scores (MD=-0.55, 95%CI=-0.81~-0.29), and improve patients’ depression and anxiety (Baker Depression Scale), MD=-2.23, 95%CI=-3.84~-0.82; Hamilton Anxiety Scale, MD=-4.25, 95%CI=-6.20~-2.29). Conclusion: Current evidence shows that CBT has a good clinical effect on reducing neuropathic pain and improving patients' depression and anxiety. It can be used as a non-drug treatment for neuropathic pain in clinics, communities and families.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis
AU  - Ding Ning
AU  - Dong Anqin
AU  - Zhang Cuicui
AU  - Zhang Lingxi
Y1  - 2022/04/22
PY  - 2022
N1  - https://doi.org/10.11648/j.sd.20221002.16
DO  - 10.11648/j.sd.20221002.16
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 60
EP  - 67
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20221002.16
AB  - Objective: A systematic review of the effectiveness of cognitive behavioral therapy (CBT) and traditional non-drug methods in the treatment of neuropathic pain and anxiety. Method: PubMed, Embase, Cochrane, PsycINFO, Wanfang Database (WANFANG), China Knowledge Network (CNKI), VIP (VIP) and China Biomedical Literature Database (CBM) were electronically searched from the establishment of the database to March 2021 to collect randomized controlled trials (RCT) of the treatment of neuropathic pain. Two researchers independently carried out literature screening, data extraction and methodological quality evaluation, and cross-checked, and used RevMan5.3 software for Meta analysis. Results: A total of 15 RCTs with 1274 subjects were included, including 606 cases in the CBT group and 668 cases in the traditional treatment group. Meta-analysis results show that, compared with traditional non-drug treatments, CBT can significantly reduce neuropathic pain scores (MD=-0.55, 95%CI=-0.81~-0.29), and improve patients’ depression and anxiety (Baker Depression Scale), MD=-2.23, 95%CI=-3.84~-0.82; Hamilton Anxiety Scale, MD=-4.25, 95%CI=-6.20~-2.29). Conclusion: Current evidence shows that CBT has a good clinical effect on reducing neuropathic pain and improving patients' depression and anxiety. It can be used as a non-drug treatment for neuropathic pain in clinics, communities and families.
VL  - 10
IS  - 2
ER  -

Copy | Download

Author Information

Ding Ning

Department of Rehabilitation, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Dong Anqin

Department of Rehabilitation, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Zhang Cuicui

Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China
Zhang Lingxi

Academy of Medical Sciences, Neihuang People’s Hospital, Anyang, China

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Ding Ning, Dong Anqin, Zhang Cuicui, Zhang Lingxi. (2022). The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis. Science Discovery, 10(2), 60-67. https://doi.org/10.11648/j.sd.20221002.16

Copy | Download

ACS Style

Ding Ning; Dong Anqin; Zhang Cuicui; Zhang Lingxi. The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis. Sci. Discov. 2022, 10(2), 60-67. doi: 10.11648/j.sd.20221002.16

Copy | Download

AMA Style

Ding Ning, Dong Anqin, Zhang Cuicui, Zhang Lingxi. The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis. Sci Discov. 2022;10(2):60-67. doi: 10.11648/j.sd.20221002.16

Copy | Download

@article{10.11648/j.sd.20221002.16,
  author = {Ding Ning and Dong Anqin and Zhang Cuicui and Zhang Lingxi},
  title = {The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis},
  journal = {Science Discovery},
  volume = {10},
  number = {2},
  pages = {60-67},
  doi = {10.11648/j.sd.20221002.16},
  url = {https://doi.org/10.11648/j.sd.20221002.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20221002.16},
  abstract = {Objective: A systematic review of the effectiveness of cognitive behavioral therapy (CBT) and traditional non-drug methods in the treatment of neuropathic pain and anxiety. Method: PubMed, Embase, Cochrane, PsycINFO, Wanfang Database (WANFANG), China Knowledge Network (CNKI), VIP (VIP) and China Biomedical Literature Database (CBM) were electronically searched from the establishment of the database to March 2021 to collect randomized controlled trials (RCT) of the treatment of neuropathic pain. Two researchers independently carried out literature screening, data extraction and methodological quality evaluation, and cross-checked, and used RevMan5.3 software for Meta analysis. Results: A total of 15 RCTs with 1274 subjects were included, including 606 cases in the CBT group and 668 cases in the traditional treatment group. Meta-analysis results show that, compared with traditional non-drug treatments, CBT can significantly reduce neuropathic pain scores (MD=-0.55, 95%CI=-0.81~-0.29), and improve patients’ depression and anxiety (Baker Depression Scale), MD=-2.23, 95%CI=-3.84~-0.82; Hamilton Anxiety Scale, MD=-4.25, 95%CI=-6.20~-2.29). Conclusion: Current evidence shows that CBT has a good clinical effect on reducing neuropathic pain and improving patients' depression and anxiety. It can be used as a non-drug treatment for neuropathic pain in clinics, communities and families.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - The Effect of Cognitive Behavioral Therapy on Neuropathic Pain: A Meta-analysis
AU  - Ding Ning
AU  - Dong Anqin
AU  - Zhang Cuicui
AU  - Zhang Lingxi
Y1  - 2022/04/22
PY  - 2022
N1  - https://doi.org/10.11648/j.sd.20221002.16
DO  - 10.11648/j.sd.20221002.16
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 60
EP  - 67
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20221002.16
AB  - Objective: A systematic review of the effectiveness of cognitive behavioral therapy (CBT) and traditional non-drug methods in the treatment of neuropathic pain and anxiety. Method: PubMed, Embase, Cochrane, PsycINFO, Wanfang Database (WANFANG), China Knowledge Network (CNKI), VIP (VIP) and China Biomedical Literature Database (CBM) were electronically searched from the establishment of the database to March 2021 to collect randomized controlled trials (RCT) of the treatment of neuropathic pain. Two researchers independently carried out literature screening, data extraction and methodological quality evaluation, and cross-checked, and used RevMan5.3 software for Meta analysis. Results: A total of 15 RCTs with 1274 subjects were included, including 606 cases in the CBT group and 668 cases in the traditional treatment group. Meta-analysis results show that, compared with traditional non-drug treatments, CBT can significantly reduce neuropathic pain scores (MD=-0.55, 95%CI=-0.81~-0.29), and improve patients’ depression and anxiety (Baker Depression Scale), MD=-2.23, 95%CI=-3.84~-0.82; Hamilton Anxiety Scale, MD=-4.25, 95%CI=-6.20~-2.29). Conclusion: Current evidence shows that CBT has a good clinical effect on reducing neuropathic pain and improving patients' depression and anxiety. It can be used as a non-drug treatment for neuropathic pain in clinics, communities and families.
VL  - 10
IS  - 2
ER  -

Copy | Download